Example sentences of "[subord] it is [adv] known " in BNC.

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1 Although it is well known nowadays that , in addition to the noxious cereal grains , genetic factors may predispose susceptible subjects to an immune response that damages the small intestinal mucosa and the other environmental factors may triggerthis abnormal immune response , it was Dicke 's astute observations some 50 years ago that first changed the prognosis and treatment of these patients dramatically .
2 The rights to Presley 's ‘ Sun ’ recordings were acquired by RCA Victor together with the rights to the artist , and although it is now known that the tapes in RCA Victor 's vault are not actually the 1955 originals , they are extremely good copies , and all have been reissued on compact disc .
3 Once it is generally known , ’ said Roland , ‘ that these letters exist , everyone will be at your door .
4 A trade usage will be imported if it is widely known and followed , and is sufficiently certain , binding and reasonable .
5 You probably already know what a larva is because it is also known as a caterpillar .
6 It is somewhat paradoxical that structural shift does not appear to have been a major factor in productivity growth after the war , because it is well known that structural imbalances contributed substantially to unemployment between the wars .
7 However it would appear that Hahnemann was a couple of centuries ahead of his time because it is now known that the DNA of certain viruses can incorporate itself into our own genome , our own inherited material .
8 While it is well known that machair may extend as much as 2 km inland in South Uist , less well known is the altitude to which blown shell sand exerts an ecological influence : the dunes at Luskentyre Banks ( NG 0699 ) are up to 35 m high , while the presence of large amounts of wind-blown shell fragments is evident from the presence of charophytes in lochs on Tairaval ( NB 1135 ) ( Angus , unpublished NCC report ) and at Mangersta ( NB 0131 ) ( Biagi et al 1985 ) , both sites being more than 50 m above sea level .
9 It may also be noted that if this method is employed then the first number chosen should be by random means rather than just ‘ saying a number between 1 and 10 ’ since it is well known that choices between these limits do not come out anything like randomly — the number 7 being particularly popular .
10 North sea operators are given dispensations , not only when there are equivalent or higher alternative arrangements in place but in some cases when it is well known to the authorities that the platforms are operating at a level that would not be allowed if they were completely new platforms .
11 In addition it was decided only to examine information that is external to the company and available from formal sources even though it is well known ( and was confirmed in discussions with the companies themselves ) that a considerable use is made of internal and informal information .
12 For example , I wonder why there are no English-speaking contributors to the Panofsky centenary conference , even though it is well known that this approach was most fully developed in the English-speaking world .
13 Desktop Sunergy Classics will run a 50MHz Tsunami ( or MicroSparc as it is officially known ( UX No 406 ) ) , and are rated at 22.6 SPECint(92) , 17.4 SPECfp(92) and around 14 MFLOPS .
14 Sasse , as it is generally known , is the oldest secondary school in the Cameroon Republic by a good ten years .
15 TVH , as it is generally known , was typified for me by a man called Alf Mignot , who died in 1987 in his early sixties .
16 Someone looking after a partner or relative with Alzheimer 's disease — or senile dementia as it is also known — has particular problems .
17 The Chardonnay is particularly prone to ‘ fan-leaf ’ or court-noué , as it is also known .
18 The threat posed by toxocariasis , or visceral larval migrans , as it is also known , is relatively slight with about 10 cases a year being recorded in England and Wales , as an example .
19 In the first , primary visual cortex , V1 or area 17 , as it is also known , there was considered to be a fairly faithful map of the retina with relatively little recoding of information having taken place between the eye and this part of the brain .
20 Pravda , the leading anti-Yeltsin newspaper in Moscow , has printed excerpts of what it claims is a memo from Mr Primakov , dated March 21st 1992 , in which the spook outlined the properties of red mercury , or mercuric salt of antimonous acid as it is also known , in detail .
21 This oracle speaks of a brother as the instrument of death , which fits with the case as it is yet known .
22 Classes at the ‘ City Lit ’ , as it is affectionately known , are handled by a highly competent team of tutors , many of whom teach at the drama schools too .
23 Only one horse , Mandarin , has won both the Gold Cup and the ‘ Grand Steep ’ as it is affectionately known .
24 I suggest that the general public also regard statements about animal tested products with caution , as it is well known that many of these products have had extremely adverse effects on human beings .
25 The last category is anyone under the influence of alcohol , as it is well known that the mental faculties of such people are often impaired , even if only temporarily .
26 This date is too late for the birth of Jesus as it is well known that Jesus was born in the reign of Herod the Great , who died in 4 BC .
27 Based on research done at Xerox 's Palo Alto Research Centre or , PARC as it is widely known , the Apple Lisa was the first commercial micro to take these concepts to the mass market .
28 The town also boasts , in its main street , a remarkable seventeenth-century mansion , the Freuler Mansion or Palace as it is locally known , built for a local man who acquired riches in the service of the French crown as a colonel of mercenaries ( a not uncommon employment for the Swiss in those days ) .
29 The terms of reference are reproduced here in full because they provide an interesting example where the overall objective behind the policy development is clear — improved financial results or , in other words , reducing the size of the state subsidy or Public Service Obligation as it is correctly known .
30 By this time , Edinburgh had emerged as the recognized centre of " the Female Question " ( as it is always known in the union literature ) .
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