Example sentences of "have a major role " in BNC.

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1 Revision of this 1966 manual would clearly have a major role in influencing local developments in the future , just as Dutch and German Government publications had propagated nationally the relevant experience gained in local experiments .
2 So the endothelins may have a major role in atherosclerosis and the reocclusion that often follows surgical opening of occluded arteries .
3 The Local Government International Bureau will have a major role to play in ensuring that local government is indeed ready .
4 They include such things as stock control , critical path analysis , and organiser programs — and may well have a major role to play in mathematics learning in the future .
5 This fact , linked to the evidence that a high proportion of defective issues are suffering from use-related types of damage — such as detached boards and loose pages — points very strongly to the conclusion that the routine vetting of material supplied to readers should have a major role to play in the selection of items for repair and refurbishment .
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