Example sentences of "[coord] it is [adv] known [conj] " in BNC.

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1 For example , there is growing evidence showing the relationship between poor housing conditions and poor health , both physical and mental , ’ and it is also known that poor housing adversely affects educational attainment , and that overcrowded conditions can lead to domestic tension and perhaps violence .
2 Only a three-yard stretch of the theatre has been unearthed , and it is not known whether any more will be excavated .
3 Firstly , it is inadvisable to take remedies consisting of mixtures as no homoeopathic provings have been done on mixtures and it is not known whether the effects of these are different from the effects of their individual components .
4 The natural history of AIDS related sclerosing cholangitis has not been clearly documented , and it is not known whether its presence has an independent influence on the prognosis of the affected patient .
5 Few of these have been specifically identified and it is not known whether any single factor is essential for the development of Crohn 's disease .
6 And it is well known that , being required to prepare designs for a useless and costly object by one of our leading nobility , long since deceased , one of princely fortune , but who had an extravagant passion for building , he purposely appealed to the son to advise his father to give the intention ’ .
7 And it is well known that children who have been read to in their preschool years have a general advantage when the learning of reading begins .
8 First , non-response was high and it is now known that , as a category , non-respondents are often very different in a number of relevant respects from those who do respond .
9 They could obtain compass information from the sun and stars , and it is indeed known that some seasonal migrators follow stellar patterns ; stellar orientation has been particularly well studied in the indigo bunting , a bird that inhabits North America .
10 Sir , the pond in D thirty nine has been shown to be a breeding place for the Great Crested Newt , but it is also known that it migrates to other ponds , several others , but does not necessarily breed there , but chooses at Skelton .
11 The National Trust is currently undertaking a structural survey which will reveal the full scale of the damage , but it is already known that extensive harm has been done to the brickwork , windows and terrace .
12 From there she could have travelled to France or Belgium but it is not known whether she boarded a ferry .
13 The police have improved both their procedures and their training , but it is not known whether social attitudes in general have changed greatly .
14 But it is not known whether TCR- β gene rearrangement or expression is required for such a transition , and no information is yet available on a role for TCR- α gene rearrangement or expression .
15 Perforated discs ( bi ) ( fig. 14 ) and the afore-mentioned zong came to designate heaven and earth , but it is not known whether this was their original meaning .
16 North American Indians , Polynesian and Micronesian Pacific islanders , Australian Aborigines , and Asian Indians are usually considered in these terms , but it is not known whether all human populations previously subject to severe ‘ feast and famine ’ conditions have a thrifty genotype .
17 The differential fee for night visits is intended to discourage general practitioners from using deputising services , but it is not known whether it has had this effect .
18 Our solutions containing rice derived glucose polymer promoted the highest water obsorption in the secretory state but it is not known whether increasing the polymer concentration ( but maintaining ORS hypotonicity ) would enhance water absorption by further stimulating active glucose transport or whether water absorption would be jeopardised , even by a moderate increase in osmolality .
19 A charter to hold a market and an annual fair was granted in 1348 , but it is not known when the use was discontinued .
20 He also exhibited in Ulverston and in his diaries talks of preparations for big shows in Manchester and Liverpool , but it is not known if these took place .
21 Amongst the items salvaged were a complete Merlin engine , propellers , guns and instruments and the Deputy Keeper of the RAF Museum , Jack Bruce , flew out to Berlin to inspect the items , but it is not known if any of the items were suitable for use .
22 Oxyradical dependent photoemission of granulocytes stimulated by platelet activating factor has been detected in vivo in rat mesenteric microvascular beds , but it is not known if these reactive oxygen species are generated in vivo in the colonic mucosa because phagocytes may be activated during isolation procedures used in in vitro studies .
23 But it is well known that the provision of advice services nationally is uneven and as the best.known generalist advice agency , the CAB feels that it would be failing the wider community if it did not consider what barriers may be preventing people from approaching a CAB for advice .
24 It is questionable whether the spaying of cows was widely practised at that time , but it is well known that London dairymen were only interested in a continuous milk supply .
25 But it is well known that there is a prejudice against awarding the bigger gongs to those who have fled England : especially for Switzerland .
26 Hyenas have always been thought of as scavengers but it is now known that they are also vigorous nocturnal hunters .
27 The details of the legend 's growth are obscure , but it is now known that it was developing steadily in northern Spain and southern France in the centuries between the eighth and the eleventh .
28 This was a time of panic , in which one farmer alleged that a thousand of his sheep had been killed by these parrots ; but it is now known that they rarely kill sheep .
29 Until quite recently it was considered that it was the crust that attained equilibrium with respect to the mantle , but it is now known that isostatic adjustments also involve the rigid mantle forming the lower part of the lithosphere .
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