Example sentences of "[conj] it [is] [adv] know " in BNC.

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1 Although it is well known nowadays that , in addition to the noxious cereal grains , genetic factors may predispose susceptible subjects to an immune response that damages the small intestinal mucosa and the other environmental factors may triggerthis abnormal immune response , it was Dicke 's astute observations some 50 years ago that first changed the prognosis and treatment of these patients dramatically .
2 Although it is not known when he will be able to return to his £350,000-a-year job , he is expected to lead a normal life within three months .
3 They arrived on Christmas Eve 1924 , proving that high-quality electrical test recordings existed at the end of 1924 , although it is not known that any of these survive today .
4 They also plan to contact local doctors and hospitals in case the man sought medical treatment for the bites , although it is not known how serious his injuries were .
5 According to Sannia and James(1977) , the place of Parorchis acanthus ( Nicoll , 1906 ) is taken by Renicola thaidus Stunkard ( 1964 ) in America and Iceland , although it is not known whether this parasite exerts similar effects on its host .
6 Although it is not known for certain whether Yazid was present at Karbala , he is cast by the Shiites as the author of the incident , and the name is to this day a favourite Shiite epithet for a Sunni adversary — it was used in this sense during the 1980s war by the Tehran leadership when referring to that in Baghdad .
7 The company has , however , gone ahead with £1 million of research into public attitudes to nuclear power and has completed filming at least one television commercial , although it is not known when it will be broadcast .
8 The Royal Navy says it will be a routine departure for them , although it is not known yet how Cammell Laird will mark the event .
9 Although it is not known if the move will put off potential customers for the Cornmill , there are already fears an existing severe shortage of parking spaces threatens the future prosperity of Darlington 's town centre .
10 She had lived there for some time although it is not known where she lived before coming to Darlington .
11 The rights to Presley 's ‘ Sun ’ recordings were acquired by RCA Victor together with the rights to the artist , and although it is now known that the tapes in RCA Victor 's vault are not actually the 1955 originals , they are extremely good copies , and all have been reissued on compact disc .
12 Editor , — Fritz H Schröder rightly emphasises that it is not known whether treatment of early prostatic cancer is beneficial or whether screening for the disease offers any advantage .
13 It will continue to fall this year and next year and I think that it is well known to everybody that this Government 's policy is to lower taxes , in contrast with the plans of the hon. Gentleman 's party .
14 My friend says I should not have been taking this drug during my pregnancy and that it is well known that it can cause these problems .
15 My friend says I should not have been taking this drug during my pregnancy and that it is well known that it can cause these problems .
16 The ancient Dwarf hold of Karak Ungor has become so infested with Night Goblins that it is now known as Red Eye Mountain .
17 So , after lunching at one of the excellent local inns , we contented ourselves with making a wide sweep South to the River Dove and back up to the Derwent , — stopping at Castleton which , with its show caves and fluorspar ( Blue John stone ) mines should n't be missed and at Eyam which was so badly ravaged by the pestilence of 1665/6 that it is still known as The Plague Village .
18 So , after lunching at one of the excellent local inns , we contented ourselves with making a wide sweep South to the River Dove and back up to the Derwent , — stopping at Castleton which , with its show caves and fluorspar ( Blue John stone ) mines should n't be missed and at Eyam which was so badly ravaged by the pestilence of 1665/6 that it is still known as The Plague Village .
19 The scarlet pimpernel is so sensitive that it is often known as the Poor Man 's Weather Glass .
20 Once it is generally known , ’ said Roland , ‘ that these letters exist , everyone will be at your door .
21 I have a reputation for honesty and fair trading — and it 's well known that I do n't have any truck with shady deals , ’ she informed him bluntly .
22 And it 's also known that breastmilk has a special value for babies most vulnerable to infection , for example those born ill or premature .
23 For example , there is growing evidence showing the relationship between poor housing conditions and poor health , both physical and mental , ’ and it is also known that poor housing adversely affects educational attainment , and that overcrowded conditions can lead to domestic tension and perhaps violence .
24 Only a three-yard stretch of the theatre has been unearthed , and it is not known whether any more will be excavated .
25 Damage was also very great in the mustelid samples , but in the one good sample from the pine marten the bones were less modified than in the canid samples , and it is not known at present which pattern is more typical of mustelids .
26 Unfortunately , the Palace had been forced to move to Herne Hill by the time the match against Bob 's old club , Croydon Common , was staged , and it is not known what arrangements were made on the players ' behalf .
27 Firstly , it is inadvisable to take remedies consisting of mixtures as no homoeopathic provings have been done on mixtures and it is not known whether the effects of these are different from the effects of their individual components .
28 It has no cellars in which material could have been stored for safety , and it is not known how much had been removed elsewhere .
29 Others were selected , and it is not known how , as the parish church for an area , in which the sacraments of baptism , marriage and burial were allowed .
30 The aminosalicylates are far less specific agents , and it is not known which of their many pharmacological actions explains their therapeutic effect in inflammatory bowel disease .
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