Example sentences of "crohn ['s] [noun sg] [conj] [prep] " in BNC.
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| 1 | Whatever the site of the biopsy , the level of platelet activating factor in colonic mucosa was higher ( p<0.01 ) in Crohn 's disease than in controls . |
| 2 | Lyso platelet activating factor and alkyl acyl glycerophosphocholine were not significantly higher in Crohn 's disease than in controls . |
| 3 | The platelet activating factor content of mucosal samples was significantly ( p<0.01 ) higher in patients with Crohn 's disease than in controls , both in the right ( 270 ( 100 ) v ( 11 ) pg/mg net weight ) and left colon ( 280 ( 110 ) v 30 ( 8 ) pg/ mgW ) ( Fig 1 ) . |
| 4 | Whatever the site of the biopsies , lyso platelet activating factor and alkyl acyl glycerophosphocholine concentrations were not significantly higher in Crohn 's disease than in controls ( 4.5 ( 1.2 ) v 3.4 ( 0.8 ) µg/mgW and 190 ( 30 ) v 180 ( 60 ) µg/mgW respectively ( Fig 2 ) . |
| 5 | The high rate of diagnostic revision ( 25% ) based on this independent , blind histopathological review may have overdiagnosed definite Crohn 's disease but in many the final diagnosis was uncertain and labelled as indeterminate colitis . |
| 6 | A progressive reduction in tissue perfusion may accompany recurrence of Crohn 's disease while at a subclinical stage . |
| 7 | Nevertheless , different HLA types have been associated with granuloma positive and granuloma negative Crohn 's disease and with other differences in manifestation of the disorder in Japan and in Italy , while the F and FS phenotypes of complement component C3 have been over-represented in Crohn 's disease patients whose small bowel is affected . |
| 8 | Second is the extent of genetic heterogeneity within Crohn 's disease and of the genetic correlation between Crohn 's disease and ulcerative colitis . |
| 9 | A positive reaction was seen in the bowel wall , both in patients with Crohn 's disease and in controls . |
| 10 | Platelet activating factor ( PAF-ACETHER or PAF ) and precursors of platelet activating factor were investigated in 26 patients with acute Crohn 's disease and in 10 healthy controls . |
| 11 | Platelet activating factor , lyso platelet activating factor , and alkyl acyl glycerophosphocholine were found in patients with acute Crohn 's disease and in remission as well as in controls . |
| 12 | Cyclosporine is an immunosuppressive drug that was found to be of benefit in a recent double blind study in Crohn 's disease and in an open study conducted in ulcerative colitis . |
| 13 | Although none of the autoantibodies have been proved to be of pathogenetic significance , it has been shown , both in Crohn 's disease and in ulcerative colitis , that IgG and complement can be present on the apical surface of enterocytes in vivo , possibly indicating a pathogenetic role for anti-epithelial/anti-brush border antibodies in inflammatory bowel disease . |
| 14 | Pouchitis developed in five ( 50% ) of the patients with definite Crohn 's disease and in five ( 50% ) of those with indeterminate colitis compared with only 16 ( 26% ) in the ulcerative colitis group . |
| 15 | Pouch excision was undertaken in two other patients with Crohn 's disease because of pouch fistulas . |
| 16 | Elemental ( aminoacid based ) diets were initially introduced as primary treatment of active Crohn 's disease because of their hypoallergenicity , because it was considered that whole protein may act as a dietary antigens and increase the immune stimuli to the gut . |