Example sentences of "[coord] it is [adv] known " in BNC.

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31 But it is not known whether TCR- β gene rearrangement or expression is required for such a transition , and no information is yet available on a role for TCR- α gene rearrangement or expression .
32 Perforated discs ( bi ) ( fig. 14 ) and the afore-mentioned zong came to designate heaven and earth , but it is not known whether this was their original meaning .
33 North American Indians , Polynesian and Micronesian Pacific islanders , Australian Aborigines , and Asian Indians are usually considered in these terms , but it is not known whether all human populations previously subject to severe ‘ feast and famine ’ conditions have a thrifty genotype .
34 The differential fee for night visits is intended to discourage general practitioners from using deputising services , but it is not known whether it has had this effect .
35 But it is not known how these skills relate to levels of proficiency or to the process of acquisition .
36 Oxyradical dependent photoemission of granulocytes stimulated by platelet activating factor has been detected in vivo in rat mesenteric microvascular beds , but it is not known if these reactive oxygen species are generated in vivo in the colonic mucosa because phagocytes may be activated during isolation procedures used in in vitro studies .
37 Our solutions containing rice derived glucose polymer promoted the highest water obsorption in the secretory state but it is not known whether increasing the polymer concentration ( but maintaining ORS hypotonicity ) would enhance water absorption by further stimulating active glucose transport or whether water absorption would be jeopardised , even by a moderate increase in osmolality .
38 But it is well known that the provision of advice services nationally is uneven and as the best.known generalist advice agency , the CAB feels that it would be failing the wider community if it did not consider what barriers may be preventing people from approaching a CAB for advice .
39 It is questionable whether the spaying of cows was widely practised at that time , but it is well known that London dairymen were only interested in a continuous milk supply .
40 But it is well known that there is a prejudice against awarding the bigger gongs to those who have fled England : especially for Switzerland .
41 Death ‘ But it is well known there needs to be a substantial realignment of production capacity . ’
42 Hyenas have always been thought of as scavengers but it is now known that they are also vigorous nocturnal hunters .
43 The details of the legend 's growth are obscure , but it is now known that it was developing steadily in northern Spain and southern France in the centuries between the eighth and the eleventh .
44 This was a time of panic , in which one farmer alleged that a thousand of his sheep had been killed by these parrots ; but it is now known that they rarely kill sheep .
45 Until quite recently it was considered that it was the crust that attained equilibrium with respect to the mantle , but it is now known that isostatic adjustments also involve the rigid mantle forming the lower part of the lithosphere .
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