Example sentences of "coeliac [noun] [noun pl] [pron] have [adv] " in BNC.

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1 Under basal conditions adenylate cyclase activity was significantly higher in homogenates of coeliac disease patients who had not been treated than in those of successfully treated patients and of control subjects ( Table I ) Forskolin stimulated adenylate cyclase activity in all the samples , whereas peptic tryptic cotazym gliadin digest ( 50 µg/ml ) significantly increased this activity only in the samples from coeliac disease patients who had not been treated .
2 Under basal conditions adenylate cyclase activity was significantly higher in homogenates of coeliac disease patients who had not been treated than in those of successfully treated patients and of control subjects ( Table I ) Forskolin stimulated adenylate cyclase activity in all the samples , whereas peptic tryptic cotazym gliadin digest ( 50 µg/ml ) significantly increased this activity only in the samples from coeliac disease patients who had not been treated .
3 In homogenates from coeliac disease patients who had not been treated peptide concentrations of 10–25 µg/ml failed to increase adenylate cyclase activity consistently , whereas concentrations of 50–200 µg/ml all stimulated the enzyme to the same degree ( Figure ) .
4 Basal guanylate cyclase activity was lower in homogenates from coeliac disease patients who had not been treated than in those from patients who had been treated and from control subjects , though the differences were not statistically significant ( Table I ) .
5 Both cAMP and cGMP values were significantly higher in duodenal mucosa homogenates from coeliac disease patients who had not been treated than in those from patients who had been treated and from control subjects ( Table II ) .
6 In coeliac disease patients who had not been treated both total and nephrogenous cAMP urinary excretion were inversely related to serum calcium values ( r=-0.759 , p<0.05 ; r=-0.876 , p<0.01 ) .
7 Our results also showed that plasma and urine cAMP and cGMP values were abnormally high in coeliac disease patients who had not been treated , and became normal only after treatment when clinical , biochemical , and histological remission was achieved .
8 As a result of the cell heterogeneity of biopsy specimens , however , it can not be excluded that inflammatory cells , widely infiltrating the mucosa of coeliac disease patients who have not been treated , also contribute to the changes of cyclic nucleotide metabolism .
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